Basic pain mechanisms / Jana Sawynok -- The physiology and basic science of bone and joints / Helen Cohen, David Blake -- NSAIDS for painful bone and joint conditions / Jennifer A. Elliott, Howard S. Smith -- Capsaicin / Gary McCleane -- Topical nitrates / Gary McCleane -- Topical analgesic options / Charles Argoff -- Intraarticular injections / William Lavelle, Elizabeth Demers, Lori Lavelle -- Nerve blocks / Elizabeth Demers, William Lavelle, Lori Lavelle -- Opioids / Gary McCleane -- Acetaminophen / Nisar Soomro -- Glucosamine / William Lavelle, Elizabeth Demers, Lori Lavelle -- Clinical pharmacology of glucocorticoids / Muhammad Munir, Jun-Ming Zhang -- Hyaluronic acid / William Lavelle, Elizabeth Demers, Lori Lavelle -- Disease modifying anti-rheumatic drugs / Lori Lavelle, William Lavelle, Elizabeth Demers -- Physical therapy / Denis Martin -- Acupuncture / Gira Patel -- Botulinum toxin / Charles Argoff -- Radiopharmaceuticals / Rahul Parikh, Howard Smith -- Muscle relaxants / Gary McCleane -- Other options / Howard Smith, Mark Guerdan -- Joint pain / Gary McCleane -- Fracture pain / Gary McCleane -- Pathophysiology and analgesic approaches to painful bone metastasis / Howard Smith, Jennifer Elliott -- Pain arising from tendons and tendon sheaths / Gary McCleane -- When is pain felt over a bone or joint, not bone or joint pain? / Gary McCleane.