Structure, physiology, and biochemistry of collagens -- Basic components of connective tissues and extracellular matrix: elastin, fibrillin, fibulins, fibrinogen, fibronectin, laminin, tenascins and thrombospondins -- Proteoglycans and diseases of soft tissues -- Advances in the use of growth factors for treatment of disorders of soft tissues -- Clinical, diagnostic, and therapeutic aspects of the Marfan syndrome -- Loeys-Dietz syndrome -- Connective tissue disorders and cardiovascular complications: the indomitable role of transforming growth factor-beta signaling -- The Ehlers-Danlos syndrome -- Ehlers-Danlos syndrome associated with glycosaminoglycan abnormalities -- Cutis laxa -- Collagen type VI myopathies -- Mouse models in tendon and ligament research -- Connective tissue disorders in domestic animals.

"This volume is a reference handbook focusing on diseases like Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome and other heritable soft connective tissue diseases. The book presents detailed information for both basic scientists and for clinicians seeing patients. It is also a stepping stone for new investigations and studies that goes beyond the facts about the composition and biochemistry of the connective tissue and extracellular matrix, as the authors connect individual components to specific aspects of various soft tissue disorders and to the actual or potential treatment of them"--