TY - BOOK AU - Hartl, Daniel L. AU - Ruvolo, Maryellen. (Author) TI - Genetics : analysis of genes and genomes SN - 9781449635961 AV - MED QH430 .H3733 PY - 2012/// CY - Burlington PB - Jones & Bartlett Learning KW - Genetic KW - Genetic Phenomena N1 - "Includes online access code"--Cover Includes index; Genes, genomes, and genetic analysis DNA structure and genetic variation Transmission genetics : the principle of segregation Chromosomes and sex-chromosome inheritance Genetic linkage and chromosome mapping Molecular biology of DNA replication and recombination Molecular organization of chromosomes Human karyotypes and chromosome behavior Genetics of bacteria and their viruses Molecular biology of gene expression Molecular mechanisms of gene regulation Genomics, proteomics, and transgenics Genetic control of development Molecular mechanisms of mutation and DNA repair Molecular genetics of the cell cycle and cancer Mitochondrial DNA and extranuclear inheritance Molecular evolution and population genetics The genetic basis of complex traits Human evolutionary genetics N2 - Hartl and Ruvolo (biology and human evolutionary biology, Harvard U.) introduce genetics and genomics to undergraduates in this longstanding textbook that has been revised and updated with recent data and includes a new chapter on human genetic evolution. They integrate transmission genetics, molecular genetics, and evolutionary genetics and detail the basic process of gene transmission, mutation, expression, and regulation, and experimental methods. Each chapter now has a beginning section on scientific competencies and learning objectives. The edition has new and updated illustrations and tables; new problems; an expanded guide to problem solving; and new sections on telomere length limits and number of cell doublings, copy-number variations with reciprocal risks of autism and schizophrenia, translation proofreading and premature termination, stochastic noise in gene and lac expression, and long non-coding RNA ER -