"Includes online access code"--Cover
Includes index

Genes, genomes, and genetic analysis
DNA structure and genetic variation
Transmission genetics : the principle of segregation
Chromosomes and sex-chromosome inheritance
Genetic linkage and chromosome mapping
Molecular biology of DNA replication and recombination
Molecular organization of chromosomes
Human karyotypes and chromosome behavior
Genetics of bacteria and their viruses
Molecular biology of gene expression
Molecular mechanisms of gene regulation
Genomics, proteomics, and transgenics
Genetic control of development
Molecular mechanisms of mutation and DNA repair
Molecular genetics of the cell cycle and cancer
Mitochondrial DNA and extranuclear inheritance
Molecular evolution and population genetics
The genetic basis of complex traits
Human evolutionary genetics

Hartl and Ruvolo (biology and human evolutionary biology, Harvard U.) introduce genetics and genomics to undergraduates in this longstanding textbook that has been revised and updated with recent data and includes a new chapter on human genetic evolution. They integrate transmission genetics, molecular genetics, and evolutionary genetics and detail the basic process of gene transmission, mutation, expression, and regulation, and experimental methods. Each chapter now has a beginning section on scientific competencies and learning objectives. The edition has new and updated illustrations and tables; new problems; an expanded guide to problem solving; and new sections on telomere length limits and number of cell doublings, copy-number variations with reciprocal risks of autism and schizophrenia, translation proofreading and premature termination, stochastic noise in gene and lac expression, and long non-coding RNA