000			01429cam a2200193 i 4500
020			_a9781461456469
050	0	0	_aMED RC280.B8 _bB868398
245	0	0	_aBreast cancer metastasis and drug resistance
260			_aNew York _bSpringer _c2013
300			_axi, 413 pages : _bill ;
520			_aThis volume comprehensively covers recent prrogress in breast cancer research. In an effort to successfully treat breast cancer, it is imperative to fully understand the disease with all its heterogeneity ; understand the factors that influence the metastasis of breast cancer to distant organs making it lethal and understand the underlying processes that lead to the phenomenon of drug-resistance making the disease particularly incurable. The book explores all of these issues, including the phenomenon of epithelial-mesenchymal-transition, cancer stem cells as well as microRNAs in an attempt to better understand the disease in connection to its heterogeneity, metastasis, drug-resistance as well as to propose novel signaling pathways for therapeutic intervention. The profiling of tumors to molecularly classify breast cancers is also investigated so that customized targeted therapies can be developed --
650		0	_aBreast
650		0	_aDrug resistance in cancer cells.
650	1	2	_aBreast Neoplasms.
650	2	2	_aDrug Resistance, Neoplasm.
650	2	2	_aNeoplasm Metastasis.
700	1		_aAhmad, Aamir,
942			_cBK
999			_c2463 _d2463