000 02542nam a22001817a 4500
020 _a9780723433248
050 _aMED RC931
_b.O73 R675
100 _aRalston, Stuart H.
245 _aOsteoporosis
260 _aLondon
_bMosby Elsevier
_c2002
300 _avi, 104p.
_bill.
500 _a Includes index
505 _a 1. Introduction 2. Definition and Epidemiology 3. Pathophysiology 3.1 Bone structure 3.2 The cells of bone 3.3 Bone matrix 3.4 Bone remodelling 3.5 Regulation of bone mass and bone loss 3.5.1 Genetics 3.5.2 Sex hormones 3.5.3 Diet 3.5.4 Exercise 3.5.5 Smoking 3.5.6 Alcohol 3.5.7 Other risk factors 3.6 Diseases and drugs 3.6.1 Chronic Inflammatory disease 3.6.2 Gastrointestinal Disease 3.6.3 Thyrotoxicosis 3.6.4 Primary Hyperparathyroidism 3.6.5 Hypogonadism 3.6.6 Corticosteroids 3.6.7 Other drugs 4. Investigation and Diagnosis 4.1 Clinical Assessment 4.2 Bone densitometry 4.3 Quantitative Ultrasound 4.4 Plain Radiographs 4.5 Other Imaging techniques 4.6 Bone turnover markers 4.7 Genetic markers 4.8 Routine Biochemistry and haematology 4.9 Bone biopsy 5. Prevention of Osteoporosis 5.1 When should preventative treatment be used? 5.1.1 Diet 5.1.2 Exercise 5.1.3 Smoking alcohol and other factors 5.1.4 Calcium and vitamin D 5.1.5 HRT 5.1.6 Raloxifene 5.1.7 Tibolone 5.1.8 Bisphosphonates (Etidronate, Alendronate, Risedronate) 5.1.9 Agents in development (Zoledronate, Ibandronate) 6. Treatment of established osteoporosis 6.1 When should treatment be given? 6.1.1 Calcium and vitamin D 6.1.2 Active vitamin D metabolites 6.1.3 Calcitonin 6.1.4 Fluoride 6.1.5 Raloxifene 6.1.6 Cyclic etidronate, 6.1.7 Alendronate, 6.1.8 Risedronate 6.1.9 Agents in development (PTH, Zoledronate, Ibandronate) 7. Corticosteroid induced osteoporosis 7.1 Pathogenesis 7.2 Investigation 7.3 Prevention and Treatment 8. Osteoporosis in men 8.1 Pathogenesis 8.2 Investigation 8.3 Treatment 9. Osteogenesis imperfecta 9.1 Pathogenesis 9.2 Investigation 9.3 Treatment 10. Rare causes of osteoporosis 11. Frequently Asked Questions 12. References Appendix 1 - Drug treatments and doses Appendix 2 - Useful addresses and websites Index
520 _aThis reference is designed by clinical specialists to assist with treatment decisions. Each title in the 'Rapid Reference' series provides standard core content combined with the additional information, such as FAQs and patient organizations, needed by the GP to provide effective patient care
650 _aOsteoporosis
700 _aKleerekoper, Michael. (author)
942 _cBK
999 _c37951
_d37951