000			01455cam a22002777a 4500
020			_a9783642335693
050	0	0	_aQP632 _bB66B68
245	0	0	_aBotulinum neurotoxins
260			_aHeidelberg ; _aNew York : _bSpringer, _cc2013.
300			_aviii, 321 p. : _bill. (some col.) ;
490	1		_aCurrent topics in microbiology and immunology,
520			_aThe extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion--
650		0	_aBotulinum toxin.
650		0	_aBotulinum toxin
650	1	2	_aBotulinum Toxins, Type A
650	2	2	_aBotulinum Toxins, Type A
650	2	2	_aNeuromuscular Agents
650	2	2	_aNeuromuscular Agents
650		4	_aBotulinum toxin -- Therapeutic use.
650		4	_aBotulinum Toxins -- therapeutic use.
650		6	_aToxines botuliniques.
650		6	_aToxines botuliniques
700	1		_aRummel, Andreas.
700	1		_aBinz, Thomas.
942			_cBK
999			_c4033 _d4033